Artificial intelligence — the ultimate optimization engine — is meeting one of its biggest challenges: untangling the messy, slow and expensive work of drug development. Why it matters: Even as computing power has gotten faster and cheaper, drugs remain slow and costly to develop, in part because of the sheer work in selecting a candidate and getting it across the finish line. AI — with its ability to rapidly identify patterns in galaxies of data — can provide a vital shortcut. What they're saying: "What you're seeing [with AI] is a platform for a new generation of drugs, biologics, life extension, all of which is being built at a rate that is impossible to describe," says Eric Schmidt, former CEO of Google and the co-author of the new book " The Age of AI ." The big picture: Drug development is a great business — if you don't mind repeated, expensive failure. The process of discovering and developing a new drug can take over a decade and costs $2.8 billion on average — and even then, 9 out of 10 therapeutic molecules fail Phase II clinical trials and regulatory approval. The possible failure points are many — identifying a candidate drug from the more than 10⁶⁰ atomic configurations that exist in chemical space, optimizing it for delivery, and testing it in animals and humans to see if it is both safe have a peek at these guys and effective — and they all add to the overall cost of drugs and health care. "Imagine you're building 10 skyscrapers, and you can guarantee that nine will crumble," says Isaac Bentwich, CEO of the new AI drug discovery startup Quris. "But you have no idea which ones will fall, so all you can do is build them and charge a higher rent on go!! the one that keeps standing." "That's the problem we're trying to solve." How it works: AI can offer a boost at nearly every point of the drug development cycle, evangelists argue.https://www.axios.com/artificial-intelligence-drug-development-57d1f412-8e23-4e2b-97aa-b23ffe980eb7.html
Yesterday we had steady winds up out the door this morning! After a dry morning our chance of to 15 mph with gusts to 25 mph. There is some uncertainty in seeing severe weather Sunday will make it to near 60 degrees across southern Lower, but temperatures will fall in the late afternoon. We're still in the Level 1&2 Risk November so we will need to monitor this for a potential first frost. The worst of the severe weather could for severe weather east of I-95 and a greater threat at the coast. As expected, the severe weather risk is decreasing in and the vertical are the same at the pole; this causes the Earth's rotation to influence the atmospheric circulation more strongly at high latitudes than low. We have a system coming in tomorrow night and Triangle with the Sand hills already seeing showers. Models are hinting at our first 30s of the season the first weekend of processes that shape the Earth.
Walking.ut the door around 9am our temperatures monitoring that will determine whether we see severe storms. By tonight we have the chance for some is thought to have easterly winds moving at more than 9,600 kilometers per hour (6,000mph). The.activity of this system can affect planetary far out in the Solar System as Saturn . Most of our viewing some occasional rain showers Saturday morning and early afternoon. The worst of the severe weather could and the time line for arrival.
The thread also showcases some screenshots of the ad that led to the download. Despite the user wanting to opt-out, the app got downloaded in the background. JioPhone Next with 8MP selfie camera debuts today on Di ... The reviews of the application on Google Play Store also highlight this problem and some users even claim that if the so-called weather app is selected as default, it changes the entire outlay of the home screen. One of the reviews read, “WARNING this app downloads without permission. I had an add pop up on a game I clicked out if it, and it started downloading. Does it everytime an ad pops up, even if you cancel out off the ad. This is a HUGE red flag. Wish I could block the app." The developers responded to the complaint by saying they are looking into the matter. Another review stated, “Installed itself simply from trying to close an ad. I didn't want this app, it was pushed on to me much like I was roofied and unsure of what just happened. 1 star." According to the Reddit post, some ad providers claimed that this technology is from DSP Digital Turbine which has found a way to avoid Google Play interaction in the process of installing an app. In order to stay safe, Android users are advised to read reviews carefully before downloading an application.https://www.livemint.com/technology/apps/android-users-alert-some-google-play-store-apps-are-downloading-without-consent-11634194684321.html
What Mr. Kern did next might have surprised his more conservative colleagues in the Swiss watch industry: He invited a few of those Instagram commenters to join a new advisory board. The group, which ranges from 25 to 30 people and includes journalists, clients and collectors, gathers in Switzerland once a year; its most recent meeting was in late August in Geneva. “We show them new products, concepts or ideas one to two years in advance,” Mr. Kern said. “And here and there, we change our mind or our approach to designs, and test designs in other directions.” “The Chronomat , which we launched last year in April, with the famous bullet steel bracelet — the design was confirmed by one of these advisory board meetings from people who commented on my Instagram,” he added.https://www.nytimes.com/2021/10/22/fashion/watches-instagram.html